Genetic and environmental influences on restrained eating behavior

Int J Eat Disord. 2009 Dec;42(8):765-72. doi: 10.1002/eat.20734.

Abstract

Objective: We examined the relative contributions of genetic and environmental influences to restrained eating.

Method: Restrained eating was assessed by the Restraint Scale in a survey mailed to all twins enrolled in the University of Washington Twin Registry. We used structural equation modeling to estimate genetic and nongenetic contributions to restrained eating.

Results: 1,196 monozygotic (MZ), 456 same-sex dizygotic (DZ) twins, and 447 opposite-sex twins were included in analyses. Restraint Scale scores were more closely correlated in MZ twins (r(male) = .55, r(female) = .55) than in same-sex DZ twins (r(male) = .31, r(female) = .19). Based on structural equation modeling, the estimated heritability for restrained eating, adjusted for body mass index (BMI) and sex, was 43% (95% confidence interval 35-50%). There was little evidence for common environmental effects.

Discussion: These results indicate an inherited component to restrained eating. Genes could influence restrained eating directly or through inherited mediators such as personality factors or tendencies to gain weight.

Publication types

  • Research Support, N.I.H., Extramural
  • Twin Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Chi-Square Distribution
  • Eating / genetics*
  • Feeding Behavior*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Biological
  • Patient Selection
  • Social Environment*
  • Surveys and Questionnaires
  • Twins, Dizygotic / genetics*
  • Twins, Monozygotic / genetics*