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Cell Metab. 2009 Aug;10(2):82-3. doi: 10.1016/j.cmet.2009.07.009.

From GH to Billy Ghrelin.

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1
Department of Metabolism and Aging, The Scripps Research Institute Florida, Jupiter, FL 33458, USA. rgsmith@scripps.edu

Abstract

The octanoylated peptide hormone ghrelin regulates episodic growth hormone release and energy balance. Work in genetically modified mice (Kirchner et al., 2009) now shows that in vivo activity of ghrelin O-acyltransferase (GOAT), responsible for ghrelin octanoylation, decreases during fasting but increases after ingesting medium-chain fatty acid triglycerides (MCT).

PMID:
19656485
DOI:
10.1016/j.cmet.2009.07.009
[Indexed for MEDLINE]
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