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Stat Methods Med Res. 2010 Feb;19(1):53-70. doi: 10.1177/0962280209105023. Epub 2009 Aug 4.

Interval censoring.

Author information

1
Department of Epidemiology and Biostatistics, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Abstract

Interval-censored failure time data occur in many medical investigations as well as other studies such as demographical and sociological studies. They include the usual right-censored failure time data as a special case but provide much more complex structure and less relevant information than the right-censored data. This article reviews some basic concepts, issues and the corresponding statistical approaches related to the analysis of interval-censored data as well as recent advances. In particular, we discuss estimation of a survival function, comparison of several treatments and regression analysis as well as competing risks analysis and truncation in the presence of interval censoring. A well-known example of interval-censored data is described and analysed to illustrate some of the statistical procedures discussed.

PMID:
19654168
PMCID:
PMC3684949
DOI:
10.1177/0962280209105023
[Indexed for MEDLINE]
Free PMC Article

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