Format

Send to

Choose Destination
See comment in PubMed Commons below
J Clin Virol. 2009 Jul;45 Suppl 1:S73-7. doi: 10.1016/S1386-6532(09)70011-3.

A comparative review of laboratory-developed tests utilizing Invader HPV analyte-specific reagents for the detection of high-risk human papillomavirus.

Author information

1
Hologic, Inc., Marlborough, MA 01752, USA. michael.stillman@hologic.com

Abstract

BACKGROUND:

Testing for human papillomavirus (HPV) has emerged as an important component of cervical cancer screening and disease management. Analytic performance (sensitivity, specificity, positive predictive value, negative predictive value, accuracy) and clinical relevance are important criteria by which any new test must be reviewed.

OBJECTIVE:

This paper compares laboratory-developed tests, utilizing Invader analyte-specific reagents (ASRs) for the detection of oncogenic HPV DNA, to the Digene Hybrid Capture 2 test (HC2). In addition to accurately identifying the presence or absence of HPV, genotyping has emerged as an important consideration for risk stratification and patient management. This paper reviews all current relevant Invader HPV literature to explain how these results shape our current understanding of the topic.

PMID:
19651372
DOI:
10.1016/S1386-6532(09)70011-3
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center