Format

Send to

Choose Destination
Arch Biochem Biophys. 2010 Jan 1;493(1):13-25. doi: 10.1016/j.abb.2009.07.019. Epub 2009 Aug 3.

Oxidation of amines by flavoproteins.

Author information

1
Department of Biochemistry, University of Texas Health Science Center, San Antonio, TX 78229, USA. fitzpatrick@biochem.uthscsa.edu

Abstract

Many flavoproteins catalyze the oxidation of primary and secondary amines, with the transfer of a hydride equivalent from a carbon-nitrogen bond to the flavin cofactor. Most of these amine oxidases can be classified into two structural families, the D-amino acid oxidase/sarcosine oxidase family and the monoamine oxidase family. This review discusses the present understanding of the mechanisms of amine and amino acid oxidation by flavoproteins, focusing on these two structural families.

PMID:
19651103
PMCID:
PMC2812625
DOI:
10.1016/j.abb.2009.07.019
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center