OBJECTIVE:

To present two cases of endometriosis in patients with Glanzmann's thrombasthenia (GT) and discuss the underlying pathophysiology of endometriosis.

DESIGN:

Case report.

SETTING:

Gynecology practice in a university teaching hospital.

PATIENT(S):

Two sisters, aged 24 and 28 years, previously diagnosed as having GT.

INTERVENTION(S):

Surgical exploration.

MAIN OUTCOME MEASURE(S):

Pathologic examination of surgical specimens was performed.

RESULT(S):

A diagnosis of endometriosis was confirmed pathologically for two sisters previously diagnosed as having GT.

CONCLUSION(S):

Women with GT seem to represent an important human model of endometriosis from which important data on the pathophysiology of endometriosis can be acquired.