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Emerg Med Clin North Am. 2009 Aug;27(3):415-22. doi: 10.1016/j.emc.2009.04.002.

Neutropenic enterocolitis.

Author information

1
Department of Emergency Medicine, Doernbecher Children's Hospital, Oregon Health & Science University, Portland, OR 97239, USA. cloutier@ohsu.edu

Abstract

Neutropenic enterocolitis, also known as typhlitis or ileocecal syndrome, is a rare but important complication of neutropenia associated with malignancy. It occurs as a result of chemotherapeutic damage to the intestinal mucosa in the context of an absolute neutropenia, and can rapidly progress to intestinal perforation, multisystem organ failure, and sepsis. Presenting signs and symptoms may include fever, abdominal pain, nausea, vomiting, and diarrhea. Rapid identification by emergency physicians and timely, aggressive medical and/or surgical intervention are the cornerstones of survival for these patients.

Republished in

PMID:
19646645
DOI:
10.1016/j.emc.2009.04.002
[Indexed for MEDLINE]

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