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J Neurosurg Pediatr. 2009 Aug;4(2):113-7. doi: 10.3171/2009.4.PEDS08321.

Surgical treatment of juvenile nasopharyngeal angiofibroma with intracranial extension. Clinical article.

Author information

1
Skull Base Surgery Service, Tel-Aviv University, Tel-Aviv, Israel.

Abstract

OBJECT:

The purpose of this study was to describe the surgical treatment and outcomes of patients with intracranial extension of juvenile nasopharyngeal angiofibroma (JNA).

METHODS:

Twenty-one patients who underwent operations for JNAs between 1994 and 2008 were enrolled in the study. Seven patients (33%) had intracranial tumor extension. The middle cranial fossa and cavernous sinus were involved in 4 patients who underwent operations via the combined infratemporal fossa-midfacial degloving approach. The anterior skull base was involved in 3 patients who underwent the subcranialmidfacial degloving approach.

RESULTS:

Complete tumor removal was achieved in all patients. Postoperative complications included 1 case of soft-tissue infection. None of the patients had tumor recurrence after a mean follow-up of 42 months (range 29-85 months). No adjuvant therapy was required in any patient.

CONCLUSIONS:

Combined approaches can be used effectively for treatment of JNAs with intracranial extension without the need for adjuvant therapy.

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PMID:
19645542
DOI:
10.3171/2009.4.PEDS08321
[Indexed for MEDLINE]

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