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Otolaryngol Head Neck Surg. 2009 Aug;141(2):172-6. doi: 10.1016/j.otohns.2009.03.019.

Importance of treatment institution in head and neck cancer radiotherapy.

Author information

1
Department of Radiation Oncology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19147, USA. greg.Kubicek@jeffersonhospital.org

Abstract

OBJECTIVE:

The treatment for head and neck cancer (HNC) often involves radiotherapy. Many HNC patients are treated at the academic center (AC) where the initial surgery or diagnosis was made. Because of the lengthy time course for radiotherapy, some patients are treated at community radiation facilities (non-AC) rather than the AC despite potential AC advantages in terms of experience and technology. Our goal is to determine if these potential AC advantages correspond to a difference in treatment outcome.

STUDY DESIGN:

Historical cohort study.

SETTING:

University of Kansas Medical Center, Kansas City, Kansas.

SUBJECTS AND METHODS:

Review of records of patients with HNC cancers evaluated at the otolaryngology (ENT) department of an AC. Each patient's information and treatment characteristics were recorded, including radiotherapy treatment venue and treatment outcome.

RESULTS:

Three hundred seventy-four patients were analyzed, 263 were treated at an AC and 101 at a non-AC. Patients treated at a non-AC were more likely to present with earlier stage tumors, be treated with radiation alone rather than chemoradiotherapy, and be treated with adjuvant rather than primary radiotherapy. There was no difference in overall survival or recurrence rates between AC and non-AC.

CONCLUSION:

Patients treated at an AC are more likely to have advanced stage tumors and receive chemoradiotherapy as their primary treatment. In analyses of matching patient subsets, there was no significant difference in patient outcomes. Patients can be treated at a non-AC without affecting outcome compared with treatment at an AC.

Comment in

PMID:
19643247
DOI:
10.1016/j.otohns.2009.03.019
[Indexed for MEDLINE]
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