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Infect Dis Obstet Gynecol. 2009;2009:473971. doi: 10.1155/2009/473971. Epub 2009 Jul 20.

Malaria at parturition in Nigeria: current status and delivery outcome.

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1
Department of Pediatrics, University of Ilorin Teaching Hospital, Ilorin 240001, Nigeria. oamokuolu@yahoo.com

Abstract

BACKGROUND:

To evaluate the current status of malaria at parturition and its impact on delivery outcome in Nigeria.

METHODS:

A total of 2500 mother-neonate pairs were enrolled at 4 sites over a 12-month period. Maternal and placental blood smears for malaria parasitaemia and haematocrit were determined.

RESULTS:

Of the 2500 subjects enrolled, 625 were excluded from analysis because of breach in study protocol. The mean age of the remaining 1875 mothers was 29.0 +/- 5.1 years. The prevalence of parasitaemia was 17% and 14% in the peripheral blood and placenta of the parturient women, respectively. Peripheral blood parasitaemia was negatively associated with increasing parity (P < .0001). Maternal age <20 years was significantly associated with both peripheral blood and placental parasitaemia. After adjusting for covariates only age <20 years was associated with placental parasitaemia. Peripheral blood parasitaemia in the women was associated with anaemia (PCV < or =30%) lower mean hematocrit (P < .0001). lower mean birth weight (P < .001) and a higher proportion of low birth weight babies (LBW), (P = .025).

CONCLUSION:

In Nigeria, maternal age < 20 years was the most important predisposing factor to malaria at parturition. The main impacts on pregnancy outcome were a twofold increase in rate of maternal anaemia and higher prevalence of LBW.

PMID:
19639046
PMCID:
PMC2715570
DOI:
10.1155/2009/473971
[Indexed for MEDLINE]
Free PMC Article
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