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Biomol NMR Assign. 2009 Jun;3(1):133-6. doi: 10.1007/s12104-009-9158-4. Epub 2009 Apr 7.

1H, 15N, 13C resonance assignment of the acyl carrier protein subunit of the Saccharomyces cerevisiae fatty acid synthase.

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1
Institute of Molecular Biology and Biophysics, ETH Zurich, 8093, Zurich, Switzerland.

Abstract

Acyl carrier proteins participate in the synthesis of fatty acids. Here we report the NMR resonances assignment of the acyl carrier protein domain of the Saccharomyces cerevisiae fatty acid synthase which corresponds to the fragment 138A-302L in the primary structure. The assignment will allow performing NMR studies with the aim to investigate the intrinsic dynamics of this protein, and to study the structural changes upon apo-holo transformation in order to unveil the mechanism of binding of the growing acyl chain.

PMID:
19636964
DOI:
10.1007/s12104-009-9158-4
[Indexed for MEDLINE]
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