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Annu Rev Med. 2009;60:307-20. doi: 10.1146/annurev.med.60.053107.103955.

Extensively drug-resistant tuberculosis: a new face to an old pathogen.

Author information

1
Section of Infectious Diseases, Yale University School of Medicine, New Haven, Connecticut 06510-8002, USA. sheela.shenoi@yale.edu

Abstract

The presence and consequences of resistance to drugs used for the treatment of tuberculosis have long been neglected. The recent detection and recognition of widespread multiple-drug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis have raised interest and concern among clinicians and public health authorities globally. In this article, we describe the current global status of drug-resistant tuberculosis. We discuss the development of resistance, current management, and strategies for control.

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