Format

Send to

Choose Destination
J Med Assoc Thai. 2009 Jul;92(7):898-902.

Comparison of surgical wound infection after preoperative skin preparation with 4% chlorhexidine [correction of chlohexidine] and povidone iodine: a prospective randomized trial.

Author information

1
Department of Surgery, Faculty of Medicine, Thammasat University, Bangkok, Thailand.

Abstract

BACKGROUND:

Antiseptic scrub and paint can reduce bacterial colonization and postoperative wound infection. Two forms of antiseptics, povidone iodine and chlorhexidine, are commonly used in the operating theater.

OBJECTIVE:

To study the efficacy of the reduction of bacterial colonization and surgical wound infection among these antiseptic.

MATERIAL AND METHOD:

Five hundred surgical patients were randomly divided into two groups. Povidone Iodine and Chlorhexidine were used for skin preparation in group 1 and 2 respectively Bacterial colonization and postoperative wound infection were examined after skin preparation. Demographic data was analyzed by student's t test; the culture result and surgical wound infection were analyzed by Mantel-Haenszel method for relative risk and 95% CI.

RESULTS:

There was a significant reduction of bacterial colonization and wound infection after skin preparation in group 2 compared with group 1.

CONCLUSION:

Colonization of bacterial and postoperative surgical wound infection were significantly reduced in the chlorhexidine group. Chlorhexidine antiseptic should be the first consideration for preoperative skin preparation.

PMID:
19626807
[Indexed for MEDLINE]

Supplemental Content

Loading ...
Support Center