Format

Send to

Choose Destination
Am J Perinatol. 2010 Feb;27(2):171-2. doi: 10.1055/s-0029-1234035. Epub 2009 Jul 22.

Malaria in pregnant woman masquerading as HELLP syndrome.

Author information

1
Department of Obstetrics and Gynecology, Hôpital Beaujon, Assistance Publique-Hôpitaux de Paris, 100, Boulevard du Général Leclerc, 92110 Clichy, France. g.ducarme@gmail.com

Abstract

Malaria may be complicated by development of thrombocytopenia, elevated liver enzymes, and/or hemolysis, which may be difficult to distinguish from HELLP (hemolytic anemia; elevated liver enzymes; low platelet count) syndrome in a pregnant patient. A 33-year-old woman developed a HELLP-like syndrome and persistent fever postpartum without symptoms of preeclampsia. A malaria blood smear was performed and was positive for Plasmodium falciparum. The patient was immediately treated with quinine. The follow-up was uneventful with total disappearance of fever and prompt resolution of biochemical signs of HELLP-like syndrome 3 days later. Malaria in a pregnant woman can masquerade as HELLP syndrome. The wide overlap in symptoms (headache, malaise, digestive symptoms) does not suggest that symptoms would be effective in differentiating malaria and preeclampsia. A recent travel in endemic area, associated with malaria blood smear and clinic examination, should be the key of the differential diagnosis.

PMID:
19626579
DOI:
10.1055/s-0029-1234035
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Georg Thieme Verlag Stuttgart, New York
Loading ...
Support Center