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Obstet Gynecol Surv. 2009 Aug;64(8):542-7. doi: 10.1097/OGX.0b013e3181ab5479.

The role of prolactin- and endometriosis-associated infertility.

Author information

1
Department of OB/GYN, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. whbdf@yahoo.com

Abstract

This review will address the current understanding of the relationship between prolactin (PRL) and endometriosis-associated infertility. Although the exact mechanisms of action of hyperprolactinemia in patients with endometriosis-associated infertility have not been clearly established, this report reviews results from relevant studies in the literature. These include serum PRL levels in endometriosis-associated infertility, PRL receptors in ectopic endometriotic tissues, basal PRL levels after TSH and Danazol (isoxazolic derivative of the synthetic steroid 5alpha-ethinyl-testosterone) therapy, peritoneal fluid and nocturnal serum PRL levels in endometriosis, infertility, and luteal phase PRL concentrations in patients with endometriosis.

TARGET AUDIENCE:

Obstetricians & Gynecologists, Family Physicians.

LEARNING OBJECTIVES:

After completion of this article, the reader should be able to explain the relationship between prolactin- and endometriosis-associated infertility, relate endometriosis with infertility, and summarize two ways in which prolactin and endometriosis may be linked in the pathophysiology of infertility.

PMID:
19624865
DOI:
10.1097/OGX.0b013e3181ab5479
[Indexed for MEDLINE]

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