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J Clin Lab Anal. 2009;23(4):210-2. doi: 10.1002/jcla.20325.

Anticardiolipin antibodies in the sera of patients with diagnosed chronic fatigue syndrome.

Author information

1
Department of Pathology, John A. Burns School of Medicine, University of Hawaii at Mânoa, Honolulu, Hawaii 96822, USA.

Abstract

Examination of anticardiolipin antibodies (ACAs) in the sera of patients clinically diagnosed with chronic fatigue syndrome (CFS) using an enzyme-linked immunoassay procedure demonstrated the presence of immunoglobulin M isotypes in 95% of CFS serum samples tested. The presence of immunoglobulin G and immunoglobulin A isotypes were also detected in a subset of the samples. Future studies will focus on elucidating whether alterations to mitochondrial inner membranes and/or metabolic functions play a possible role in the expression of ACAs.

PMID:
19623655
DOI:
10.1002/jcla.20325
[Indexed for MEDLINE]

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