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Arq Neuropsiquiatr. 2009 Jun;67(2B):480-7.

Regional cooling for reducing brain temperature and intracranial pressure.

Author information

1
Intensive and Critical Medicine, Neurosurgical Intensive Care Unit, Hospital Meridional, Real e Benemérita Sociedade Portuguesa de Beneficência de São Paulo, São Paulo, SP, Brazil. fortelv@uol.com.br

Abstract

OBJECTIVE:

To evaluate the effectiveness of regional cooling for reducing brain temperature (BrTe) and intracranial pressure (ICP) in patients where conventional clinical treatment has failed.

METHOD:

Regional cooling was carried out using ice bags covering the area of the craniectomy (regional method) in 23 patients. The BrTe and ICP were determined using a fiber optic sensor. Thirteen patients (56.52%) were female. The ages ranged from 16 to 83 years (mean of 48.9). The mean APACHE II score was 25 points (11-35). The patients were submitted, on mean, to 61.7 hours (20-96) of regional cooling.

RESULTS:

There was a significant reduction in mean BrTe (p<0.0001--from 37.1 degrees C to 35.2 degrees C) and mean ICP (p=0.0001--from 28 mmHg to 13 mmHg).

CONCLUSION:

Our results suggest that mild brain hypothermia induced by regional cooling was effective in the control of ICP in patients who had previously undergone decompressive craniectomy.

PMID:
19623447
[Indexed for MEDLINE]
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