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AJR Am J Roentgenol. 2009 Aug;193(2):304-13. doi: 10.2214/AJR.09.2869.

Imaging of tumor angiogenesis: functional or targeted?

Author information

1
Molecular Imaging Program, National Cancer Institute, National Institutes of Health, 10 Center Dr., MSC 1182, Bldg. 10, Rm. 1B40, Bethesda, MD 20892-1088, USA.

Abstract

OBJECTIVE:

Angiogenesis--the growth of new vessels--is both a normal physiologic response and a critical step in many pathologic processes, particularly cancer. Imaging has long relied on the different enhancement characteristics of cancer compared with normal tissue; the information generated is often primarily morphologic and qualitative. However, more quantitative methods based on functional and targeted imaging have recently emerged.

CONCLUSION:

In this article, we review both functional and targeted imaging techniques for assessing tumor angiogenesis.

PMID:
19620425
PMCID:
PMC3523171
DOI:
10.2214/AJR.09.2869
[Indexed for MEDLINE]
Free PMC Article

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