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Virol J. 2009 Jul 20;6:111. doi: 10.1186/1743-422X-6-111.

Challenging complications of treatment--human herpes virus 6 encephalitis and pneumonitis in a patient undergoing autologous stem cell transplantation for relapsed Hodgkin's disease: a case report.

Author information

1
Department of Internal Medicine III - Hematology/Oncology, University of Ulm, Ulm, Germany. martin.bommer@uniklinik-ulm.de

Abstract

BACKGROUND:

Reactivation of human herpesvirus 6 (HHV-6) occurs frequently in patients after allogeneic stem cell transplantation and is associated with bone-marrow suppression, enteritis, pneumonitis, pericarditis and also encephalitis. After autologous stem cell transplantation or intensive polychemotherapy HHV-6 reactivation is rarely reported.

CASE REPORT:

This case demonstrates a severe symptomatic HHV-6 infection with encephalitis and pneumonitis after autologous stem cell transplantation of a patient with relapsed Hodgkin's disease.

CONCLUSION:

Careful diagnostic work up in patients with severe complications after autologous stem cell transplantation is mandatory to identify uncommon infections.

PMID:
19619326
PMCID:
PMC2718875
DOI:
10.1186/1743-422X-6-111
[Indexed for MEDLINE]
Free PMC Article

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