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J Child Neurol. 2009 Jul;24(7):846-51. doi: 10.1177/0883073808331082.

Growth patterns in children with intrauterine growth retardation and their correlation to neurocognitive development.

Author information

1
Institute for Child Development and Pediatric Neurology Unit, Tel Aviv Sourasky Medical Center affiliated to the Sackler Faculty of Medicine, Tel Aviv University, Israel. afatal@post.tau.ac.il

Abstract

The relationship between somatic growth and neurocognitive outcome was studied in a cohort of 136 children with intrauterine growth retardation. The children were followed up from birth to 9 to 10 years of age by annual measurements of growth parameters, neurodevelopmental evaluations, and IQ. The rate of catch-up for height between 1 and 2 years of age was significantly higher than the catch-up for weight (P < .001). The cognitive outcome at 9 to 10 years correlated with head circumference at all ages. The neurodevelopmental outcome at 9 to 10 years correlated with weight at all ages. Correlation with head circumference was more significant with IQ, while with weight it was stronger with the neurodevelopmental score. Height at 1 year was a significant predictor for IQ and neurodevelopmental outcome at 9 to 10 years. These findings are of distinct importance for prediction of subsequent neurodevelopmental outcome in children with intrauterine growth retardation.

PMID:
19617460
DOI:
10.1177/0883073808331082
[Indexed for MEDLINE]

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