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Zhonghua Yi Xue Za Zhi. 2009 May 19;89(19):1305-8.

[Value of intra-operative ultrasound in detecting the boundaries of intra cranial gliomas].

[Article in Chinese]

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  • 1Department of Neurosurgery, Department of Ultrasound, Beijing Tiantan Hospital, Affiliated China Capital Medical University, Beijing 100050, China.



To evaluate the application of intra-operative ultrasound (IOUS) in detecting the boundaries of intracranial gliomas.


One hundred and five consecutive patients with supra-tentorial glioma were included, male: 42 cases, female: 46 cases, age ranged from 15 - 67 years (mean 41 yrs), intra-operative ultrasound B was used to detect tumour boundaries before and after resection in 88 cases, tissues with suspicious echo was taken for verification by histological examination. And repeated MRI scan was received within 3 day after operation to judge the resection extent. The result was judged by Ultrasound doctor, neurosurgeon and pathologist, respectively.


Eighty-eight patients were operated assisted by IOUS B. Tumour was nearly total removed in 83 cases and subtotal removed in 5 cases. Histological examination showed WHO Grade II 30 cases, Grade III 31 cases and Grade IV 27 cases. One hundred and twenty samples were taken and 101 were verified as tumours. And residual tumours were found in 17 cases and brain contusion and laceration was found in 1 case. The sensitivity of IOUS was 80.1% and the specificity was 69.8%.


IOUS could produce a marked effect in judging boundaries of glioma, especially in low grade gliomas. IOUS could be a routine technique in intracranial glioma operation.

[PubMed - indexed for MEDLINE]
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