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Rev Obstet Gynecol. 2009 Spring;2(2):76-83.

Recurrent pregnancy loss: etiology, diagnosis, and therapy.

Abstract

Spontaneous pregnancy loss is a surprisingly common occurrence, with approximately 15% of all clinically recognized pregnancies resulting in pregnancy failure. Recurrent pregnancy loss (RPL) has been inconsistently defined. When defined as 3 consecutive pregnancy losses prior to 20 weeks from the last menstrual period, it affects approximately 1% to 2% of women. This review highlights the current understanding of the various etiologies implicated in RPL, including factors known to be causative, as well as those implicated as possible causative agents. The appropriate diagnostic evaluation, therapy, and prognosis are also addressed.

KEYWORDS:

Habitual abortion; Recurrent pregnancy loss; Spontaneous abortion

PMID:
19609401
PMCID:
PMC2709325

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