Send to

Choose Destination
J Immunol Methods. 1991 Nov 5;144(1):63-7.

A new qualitative method for detecting IgD in unconcentrated cerebrospinal fluid.

Author information

Department of Special Chemical Pathology, National Hospital for Neurology and Neurosurgery, London, U.K.


We report a method which is capable of demonstrating the isoelectric focusing (IEF) pattern of immunoglobulin D in unconcentrated cerebrospinal fluid (CSF) samples containing as little as 0.1-0.5 ng of total IgD. The method used was an immuno-sandwich technique, with alkaline phosphatase enzyme amplification. Oligoclonal and polyclonal IgD patterns were seen in CSF samples. No cross-reactivity with other immunoglobulins (IgG, IgA and IgM) was detected.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center