Send to

Choose Destination
See comment in PubMed Commons below
Appl Immunohistochem Mol Morphol. 2009 Dec;17(6):557-62. doi: 10.1097/PAI.0b013e3181a3b8b8.

Desmoplastic small round cell tumor of the kidney mimicking Wilms tumor: a case report and review of the literature.

Author information

Department of Urology, School of Medicine, UNESP, Botucatu, SP, Brazil.


Desmoplastic small round cell tumor (DSRCT) is a rare, aggressive, malignant neoplasm usually present with the widespread abdominal serosal involvement and affects mainly adolescents and young adults. When presenting within visceral organs, as kidney, the diagnosis of DSRCT imposes significant difficulties. We present a case of primary DSRCT of the kidney in a 10-year-old boy mimicking clinically and pathologically Wilms tumor. The tumor showed morphologic and immunohistochemical features of DSRCT and the presence of the Ewing sarcoma and Wilm tumor 1 fusion transcripts resulting from the t(11;22) (p13;q12) reciprocal translocation. DSRCT should be considered in the differential diagnosis of Wilm tumor and other small blue-round cell tumors of the kidney.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wolters Kluwer
    Loading ...
    Support Center