Format

Send to

Choose Destination
Methods Mol Biol. 2009;563:197-218. doi: 10.1007/978-1-60761-175-2_11.

Kinetic modeling as a tool to integrate multilevel dynamic experimental data.

Author information

1
Institute for Systems Biology SPb, Moscow, Russia.

Abstract

The metabolic networks are the most well-studied biochemical systems, with an abundance of in vitro and in vivo data available for quantitative estimation of its kinetic parameters. In this chapter, we present our approach to developing mathematical description of metabolic pathways. The model-based integration of reaction kinetics and the utilization of different types of experimental data including temporal dependencies have been described in detail. Software package DBSolve7 which allows us to develop kinetic model of the biochemical system and integrate experimental data has been presented.

PMID:
19597787
DOI:
10.1007/978-1-60761-175-2_11
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center