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Science. 2009 Jul 10;325(5937):204-6. doi: 10.1126/science.1172705.

Discovery of swine as a host for the Reston ebolavirus.

Author information

1
Foreign Animal Disease Diagnostic Laboratory, National Veterinary Services Laboratories, Animal and Plant Health Inspection Services, United States Department of Agriculture, Plum Island Animal Disease Center, New York, NY 11944, USA.

Abstract

Since the discovery of the Marburg and Ebola species of filovirus, seemingly random, sporadic fatal outbreaks of disease in humans and nonhuman primates have given impetus to identification of host tropisms and potential reservoirs. Domestic swine in the Philippines, experiencing unusually severe outbreaks of porcine reproductive and respiratory disease syndrome, have now been discovered to host Reston ebolavirus (REBOV). Although REBOV is the only member of Filoviridae that has not been associated with disease in humans, its emergence in the human food chain is of concern. REBOV isolates were found to be more divergent from each other than from the original virus isolated in 1989, indicating polyphyletic origins and that REBOV has been circulating since, and possibly before, the initial discovery of REBOV in monkeys.

PMID:
19590002
DOI:
10.1126/science.1172705
[Indexed for MEDLINE]
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