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Cancer Cell. 2009 Jul 7;16(1):7-8. doi: 10.1016/j.ccr.2009.06.011.

Pancreatic cancer--could it be that simple? A different context of vulnerability.

Author information

1
Translational Genomics Research Institute, Phoenix, AZ 85004, USA. dvh@tgen.org

Abstract

In a recent issue of Science, Olive and colleagues document that inhibition of Hedgehog (Hh) signaling in a genetically engineered mouse model of pancreatic cancer can enhance the intratumor concentration of certain anticancer drugs. Could this finding provide us with a new method to attack pancreatic cancer?

PMID:
19573807
DOI:
10.1016/j.ccr.2009.06.011
[Indexed for MEDLINE]
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