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J Gen Virol. 2009 Oct;90(Pt 10):2413-7. doi: 10.1099/vir.0.012344-0. Epub 2009 Jul 1.

Identification of a novel human gammapapillomavirus species.

Author information

1
Blood Systems Research Institute, San Francisco, CA 94118, USA.

Abstract

By using random PCR amplification, shotgun sequencing and sequence similarity searches, we analysed nucleic acids present in cell cultures inoculated with samples from unexplained cases of encephalitis. We identified a divergent human papillomavirus (HPV) sequence originating from a rectal swab. The full genome was amplified by inverse PCR and sequenced. The prototype of the sixth gammapapillomavirus species, HPV116, was not found in the patient's cerebrospinal fluid or respiratory secretions, nor in culture supernatants from other unexplained cases of encephalitis, indicating that its identification in an encephalitis patient was accidental.

PMID:
19570953
PMCID:
PMC2832751
DOI:
10.1099/vir.0.012344-0
[Indexed for MEDLINE]
Free PMC Article

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