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Neurosurg Focus. 2009 Jul;27(1):E9. doi: 10.3171/2009.4.FOCUS0974.

Human neocortical electrical activity recorded on nonpenetrating microwire arrays: applicability for neuroprostheses.

Author information

1
Department of Electrical and Computer Engineering, University of Utah, Salt Lake City, Utah, USA.

Abstract

OBJECT:

The goal of this study was to determine whether a nonpenetrating, high-density microwire array could provide sufficient information to serve as the interface for decoding motor cortical signals.

METHODS:

Arrays of nonpenetrating microwires were implanted over the human motor cortex in 2 patients. The patients performed directed stereotypical reaching movements in 2 directions. The resulting data were used to determine whether the reach direction could be distinguished through a frequency power analysis.

RESULTS:

Correlation analysis revealed decreasing signal correlation with distance. The gamma-band power during motor planning allowed binary classification of gross directionality in the reaching movements. The degree of power change was correlated to the underlying gyral pattern.

CONCLUSIONS:

The nonpenetrating microwire platform showed good potential for allowing differentiated signals to be recorded with high spatial fidelity without cortical penetration.

PMID:
19569897
PMCID:
PMC2941644
DOI:
10.3171/2009.4.FOCUS0974
[Indexed for MEDLINE]
Free PMC Article

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