Send to

Choose Destination
See comment in PubMed Commons below
Dis Aquat Organ. 2009 Apr 27;84(3):219-28. doi: 10.3354/dao02057.

Route of entry and tissue distribution of Yersinia ruckeri in experimentally infected rainbow trout Oncorhynchus mykiss.

Author information

Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.


Yersinia ruckeri is the causative agent of enteric redmouth disease, which leads to significant losses in salmonid aquaculture worldwide. Despite the significance of the disease, little information is available on the pathogenesis. In this study, the portal of entry was investigated using a contact-exposure infection method in rainbow trout Oncorhynchus mykiss with 4 different Y. ruckeri strains. Bacteriological and histological examination revealed the presence of high numbers of bacteria in the gills immediately after infection resulting in a rapid spread of Y. ruckeri in the internal organs. However, only a virulent strain was able to survive and multiply in the host, causing septicaemia and death several days after infection. These findings indicate that gills may be an important site of entry and that Y. ruckeri virulence is related to immune evasion.

[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Inter-Research Science Center
    Loading ...
    Support Center