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Cell. 2009 Jun 26;137(7):1183-5. doi: 10.1016/j.cell.2009.06.009.

Closing in on mechanisms of tissue morphogenesis.

Author information

1
IBDML, UMR6216 CNRS-Université de la Méditerranée, Campus de Luminy case 907, 13288 Marseille Cedex 09, France.

Abstract

It remains largely unknown how large-scale tissue movements during development emerge from the interplay of different tensile forces associated with actomyosin networks. Solon et al. (2009) now report that a ratchet-like mechanism drives the movement of epithelial sheets during dorsal closure in embryos of the fruit fly Drosophila.

PMID:
19563750
DOI:
10.1016/j.cell.2009.06.009
[Indexed for MEDLINE]
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