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Chem Commun (Camb). 2009 Jul 7;(25):3693-5. doi: 10.1039/b902455g. Epub 2009 May 29.

Antibacterial cyclic D,L-alpha-glycopeptides.

Author information

1
Department of Chemistry and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Abstract

We report the design, synthesis, membrane activity, biophysical characterization, and in vitro antibacterial activities of cationic cyclic D,L-alpha-glycopeptides bearing d-glucosamine (GlcNH(2)), D-galactose (Gal), or D-mannose (Man) glycosyl side chains.

PMID:
19557251
PMCID:
PMC2758689
DOI:
10.1039/b902455g
[Indexed for MEDLINE]
Free PMC Article

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