Send to

Choose Destination
Opt Express. 2007 May 14;15(10):6167-76.

Optical gradient flow focusing.

Author information

Department of Chemistry, University of Washington, Seattle, WA 98195-1700, USA.


This paper describes a new method for carrying out flow cytometry, which employs optical gradient forces to guide and focus particles in the fluid flow. An elliptically shaped Gaussian beam was focused at the center of a microchannel to exert radiation pressure on suspended nanoparticles that are passing through the channel, such that these particles are guided to the center of the channel for efficient detection and sorting. To verify the efficiency of this optical-gradient-flow-focusing method, we present numerical simulations of the trajectories of the nanoparticles in both electroosmotic flow (EOF) and pressure-driven flow (PDF).


Supplemental Content

Full text links

Icon for Optical Society of America
Loading ...
Support Center