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J Am Acad Dermatol. 2009 Jul;61(1):88-93. doi: 10.1016/j.jaad.2008.10.054.

Acquired bilateral nevus of Ota-like macules (Hori nevus): etiologic and therapeutic considerations.

Author information

1
Wellman Center for Photomedicine, Department of Dermatology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.

Abstract

BACKGROUND:

Acquired bilateral nevus of Ota-like macules (ABNOM), also known as Hori nevus, is one of the most commonly acquired dermal facial melanocytoses among people with dark skin, especially Asian women.

OBJECTIVE:

The goals of this article were to review published work on ABNOM; address controversies about pathogenesis and therapeutic approach; and inspire further study.

METHODS:

Articles in the literature related to the description of ABNOM were extracted and summarized.

RESULTS:

Clinically, ABNOM occurs predominantly on the face of middle-aged women. Histologically, it is characterized by irregularly shaped, bipolar melanocytes dispersed through the mid to papillary dermis. Therapeutically, various pigment-targeting lasers have emerged as the major mode of treatment.

LIMITATIONS:

There is a notable absence of both biological insight into the cause of ABNOM and robust trials to effectively define a standardized therapy. The scattered reports in the literature preclude a more rigorous meta-analytical approach.

CONCLUSION:

Although there have been many reports on ABNOM since 1984, the pathogenesis still remains unclear and controversial, and treatment of ABNOM is still challenging.

PMID:
19539841
DOI:
10.1016/j.jaad.2008.10.054
[Indexed for MEDLINE]

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