Diacylglycerol kinase alpha, from negative modulation of T cell activation to control of cancer progression

Adv Enzyme Regul. 2009;49(1):174-88. doi: 10.1016/j.advenzreg.2009.01.003.

Authors

Isabel Mérida¹, Antonia Avila-Flores, Job García, Ernesto Merino, María Almena, Pedro Torres-Ayuso

Affiliation

¹ Department of Immunology and Oncology, Centro Nacional de Biotecnología/CSIC, Darwin 3, Campus de Cantoblanco, E-28049 Madrid, Spain. imerida@cnb.csic.es

PMID: 19534031
DOI: 10.1016/j.advenzreg.2009.01.003

No abstract available

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Cell Movement
Cell Proliferation
Diacylglycerol Kinase / genetics
Diacylglycerol Kinase / metabolism*
Diglycerides / metabolism
Gene Expression Regulation, Enzymologic
Isoenzymes / genetics
Isoenzymes / metabolism
Lymphocyte Activation*
Neoplasms* / pathology
Neoplasms* / physiopathology
Phosphorylation
Protein-Tyrosine Kinases / metabolism
RNA, Messenger / genetics
RNA, Messenger / metabolism
Signal Transduction / physiology
T-Lymphocytes / physiology*
Tumor Suppressor Protein p53 / metabolism

Substances

Diglycerides
Isoenzymes
RNA, Messenger
Tumor Suppressor Protein p53
Diacylglycerol Kinase
Protein-Tyrosine Kinases