Format

Send to

Choose Destination
Cardiovasc Ultrasound. 2009 Jun 16;7:26. doi: 10.1186/1476-7120-7-26.

Hypertrophic cardiomyopathy with midventricular obstruction and apical aneurysm formation in a single family: case report.

Author information

1
Cardiology Department, Aristotle University of Thessaloniki, Greece. efthymos@med.auth.gr

Abstract

BACKGROUND:

Hypertrophic cardiomyopathy (HCM) is an extremely heterogeneous disease. An under recognized and very often missed subgroup within this broad spectrum concerns patients with left ventricular (LV) apical aneurysms in the absence of coronary artery disease.

CASE PRESENTATION:

We describe a case of HCM with midventricular obstruction and apical aneurysm formation in 3 patients coming from a single family. This HCM pattern was detected by 2D-echocardiography and confirmed by cardiac magnetic resonance imaging. A cardioverter defibrillator was implanted in one of the patients because of non-sustained ventricular tachycardia detected in 24-h Holter monitoring and an abrupt drop in systolic blood pressure during maximal exercise test. The defibrillator activated 8 months after implantation by suppression of a ventricular tachycardia providing anti-tachycardia pacing. The patient died due to refractory heart failure 2 years after initial evaluation. The rest of the patients are stable after a 2.5-y follow-up period.

CONCLUSION:

The detection of apical aneurysm by echocardiography in HCM patients may be complicated. Ventricular tachycardia arising from the scarred aneurysm wall may often occur predisposing to sudden death.

PMID:
19527529
PMCID:
PMC2706214
DOI:
10.1186/1476-7120-7-26
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for BioMed Central Icon for PubMed Central
Loading ...
Support Center