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Intern Med. 2009;48(12):1047-9. Epub 2009 Jun 15.

Thyroid hemiagenesis with Graves' disease, Graves' ophthalmopathy and multinodular goiter.

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Division of Endocrinology and Metabolism, Selcuk University, Meram School of Medicine, Konya, Turkey.


Thyroid hemiagenesis is a rare congenital anomaly in which one of the thyroid lobes with or without isthmus fails to develop. Here we present a woman patient with thyroid hemiagenesis, Graves' disease and ophthalmopathy with nodular goiter. Fine needle aspiration biopsy of the dominant nodule was suspicious of malignancy. The patient was referred for surgery for total thyroidectomy. Histopathological examination of the surgical material revealed benign features. The present case confirms that, although rare, a number of concomitant thyroid disorders can exist in a single patient with thyroid hemiagenesis just as it is seen for a normally developed thyroid gland.

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