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Brain Lang. 2009 Oct;111(1):61-5. doi: 10.1016/j.bandl.2009.05.002. Epub 2009 Jun 13.

Atypical cerebral lateralisation in adults with compensated developmental dyslexia demonstrated using functional transcranial Doppler ultrasound.

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University of Oxford, Department of Experimental Psychology, OX1 3UD, United Kingdom.


Functional transcranial Doppler ultrasound (fTCD) is a relatively new and non-invasive technique that assesses cerebral lateralisation through measurements of blood flow velocity in the middle cerebral arteries. In this study fTCD was used to compare functional asymmetry during a word generation task between a group of 30 dyslexic adults and a group of 30 non-dyslexic individuals. In light of previous evidence of atypical laterality in dyslexia, a reduced leftward asymmetry was predicted and confirmed. We know from previous research that most people with atypical language lateralisation have normal language and literacy skills: nevertheless, our results confirm that language laterality is reduced in those with dyslexia. Theoretical explanations for this apparent conundrum are discussed.

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