Format

Send to

Choose Destination
Cell. 2009 Jun 12;137(6):987-8. doi: 10.1016/j.cell.2009.05.033.

Mu and delta opioid receptors diverge.

Author information

1
Neural Plasticity Research Group, Department of Anesthesia and Critical Care, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA. cwoolf@partners.org

Abstract

Contrary to current models, Scherrer et al. (2009) provide evidence that mu and delta opioid receptors are not expressed by the same pain-sensing neurons. In mice, agonists for these receptors produce analgesia restricted to either noxious heat or mechanical stimuli, implying that the receptors act on distinct fibers to mediate completely different types of pain relief.

PMID:
19524498
DOI:
10.1016/j.cell.2009.05.033
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center