Send to

Choose Destination
Atherosclerosis. 2009 Dec;207(2):530-3. doi: 10.1016/j.atherosclerosis.2009.05.009. Epub 2009 May 21.

Effect of exercise training on cardiometabolic risk markers among sedentary, but metabolically healthy overweight or obese post-menopausal women with elevated blood pressure.

Author information

Centre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec, Québec, Canada.



To investigate the effect of exercise training on markers of the lipoprotein-lipid profile and inflammatory markers in post-menopausal overweight/obese women with a moderately elevated systolic blood pressure.


A total of 267 women [mean body mass index (BMI)=32.0+/-5.7kg/m(2) and mean age=57.3+/-6.6 years] underwent a 6-month exercise intervention program. Exercise training was performed 3-4 times per week at a targeted heart rate corresponding to 50% of the maximal oxygen consumption.


Compared to baseline values, mean change in relative VO(2) max (the primary endpoint) was of 1.18+/-2.25mL/minkg (p<0.0001), mean weight loss was of 1.4+/-3.3kg (p<0.0001), mean reduction in waist circumference was of 2.4+/-6.9cm (p<0.0001) and systolic blood pressure did not change significantly (-1.2+/-13.0mmHg, NS). No changes were observed in markers of the lipoprotein-lipid profile. No changes were observed for plasma levels of C-reactive protein, interleukin-6, tumor-necrosis factor-alpha and adiponectin. Changes in VO(2) max were negatively associated with changes in body weight (r=-0.26, p<0.0001) and waist circumference (r=-0.16, p=0.01), but not with changes in cardiometabolic risk markers.


Although exercise training significantly increased cardiorespiratory fitness in these sedentary, but metabolically healthy obese/overweight women with a moderately elevated systolic blood pressure, no significant improvements were observed in their cardiometabolic risk profile.

[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center