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Chem Commun (Camb). 2009 Jun 28;(24):3551-3. doi: 10.1039/b903993g. Epub 2009 May 7.

G-quadruplex-based DNAzyme for sensitive mercury detection with the naked eye.

Author information

1
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.

Abstract

Hg(2+) is able to inhibit the peroxidase-like DNAzyme function of a T-containing G-quadruplex DNA via Hg(2+)-mediated T-T base pairs, which enables the visual detection of Hg(2+) in the TMB-H(2)O(2) reaction system with high selectivity and sensitivity.

PMID:
19521604
DOI:
10.1039/b903993g
[Indexed for MEDLINE]
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