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IEEE Trans Med Imaging. 2009 Oct;28(10):1560-75. doi: 10.1109/TMI.2009.2020734. Epub 2009 Jun 10.

Trabecular bone analysis in CT and X-ray images of the proximal femur for the assessment of local bone quality.

Author information

1
Department of Medical Image Analysis, Universityfor Health Sciences, Medical Informatics and Technology, 6060 Hall in Tirol, Austria. karl.fritscher@umit.at

Abstract

Currently, conventional X-ray and CT images as well as invasive methods performed during the surgical intervention are used to judge the local quality of a fractured proximal femur. However, these approaches are either dependent on the surgeon's experience or cannot assist diagnostic and planning tasks preoperatively. Therefore, in this work a method for the individual analysis of local bone quality in the proximal femur based on model-based analysis of CT- and X-ray images of femur specimen will be proposed. A combined representation of shape and spatial intensity distribution of an object and different statistical approaches for dimensionality reduction are used to create a statistical appearance model in order to assess the local bone quality in CT and X-ray images. The developed algorithms are tested and evaluated on 28 femur specimen. It will be shown that the tools and algorithms presented herein are highly adequate to automatically and objectively predict bone mineral density values as well as a biomechanical parameter of the bone that can be measured intraoperatively.

PMID:
19520636
DOI:
10.1109/TMI.2009.2020734
[Indexed for MEDLINE]

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