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J Clin Neurol. 2007 Mar;3(1):62-6. doi: 10.3988/jcn.2007.3.1.62. Epub 2007 Mar 20.

Reversible verbal and visual memory deficits after left retrosplenial infarction.

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Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.


The retrosplenial cortex is a cytoarchitecturally distinct brain structure located in the posterior cingulate gyrus and bordering the splenium, precuneus, and calcarine fissure. Functional imaging suggests that the retrosplenium is involved in memory, visuospatial processing, proprioception, and emotion.We report on a patient who developed reversible verbal and visual memory deficits following a stroke. Neuropsychological testing revealed both anterograde and retrograde memory deficits in verbal and visual modalities. Brain diffusion-weighted and T2-weighted magnetic resonance imaging (MRI) demonstrated an acute infarction of the left retrosplenium.

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