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Langmuir. 2009 Jun 16;25(12):6793-9. doi: 10.1021/la9003142.

Polyelectrolyte-coated unilamellar nanometer-sized magnetic liposomes.

Author information

1
Jacobs University Bremen, Campus Ring 1, 28725 Bremen, Germany.

Abstract

Superparamagnetic nanoparticles were encapsulated in liposomes prior to the stepwise adsorption of polyelectrolytes of opposite charges commonly known as the layer-by-layer (LbL) technique. Magnetic fields allow a fast separation of coated liposomes from unbound polyelectrolytes. The coated particles were characterized by dynamic light scattering (DLS), cryo-TEM, AFM, and zeta-potential techniques. The presence of magnetic nanoparticles and the polyelectrolyte shell opens the possibility of their magnetic manipulation and targeting by applying an external magnetic or electric field.

PMID:
19505158
DOI:
10.1021/la9003142
[Indexed for MEDLINE]

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