Abstract
A boron-dipyrromethene (BODIPY) derivative containing a tridentate diaza-oxa ligand (8H-BDP) was synthesized as a fluorescent turn-on chemosensor for Hg(2+) with high sensitivity (detection limit < or = 2 ppb), a rapid response time (< or = 5 seconds) and specific selectivity over other cations under physiological conditions and in live cells according to the confocal fluorescence microscopy experiment.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Boron Compounds / chemical synthesis
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Boron Compounds / chemistry*
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Boron Compounds / metabolism
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Cell Survival
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Crystallography, X-Ray
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Drug Design
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Fluorescent Dyes / analysis
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Fluorescent Dyes / chemical synthesis
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Fluorescent Dyes / chemistry*
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HeLa Cells
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Humans
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Intracellular Space / metabolism
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Magnetic Resonance Spectroscopy
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Mass Spectrometry
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Mercury / analysis*
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Mercury / chemistry
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Mercury / metabolism
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Water / chemistry
Substances
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8-(3-N-(2-pyridylmethyl)amino-4-hydroxyphenyl)-4,4-difluoro-1,3,5,7-tetramethyl-4-bora-3a,4a-diaza-s-indacene
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Boron Compounds
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Fluorescent Dyes
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Water
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Mercury