Revival of deuterium-labeled reagents for protein quantitation

Dexing Zeng; Shuwei Li

doi:10.1039/b906335h

Revival of deuterium-labeled reagents for protein quantitation

Chem Commun (Camb). 2009 Jun 21:(23):3369-71. doi: 10.1039/b906335h. Epub 2009 May 19.

Authors

Dexing Zeng¹, Shuwei Li

Affiliation

¹ Center for Advanced Research in Biotechnology, University of Maryland Biotechnology Institute, Rockville, MD 20850, USA.

PMID: 19503873
DOI: 10.1039/b906335h

Abstract

A group of deuterium-labeled molecules that can be used for MS-based protein quantitation are synthesized, providing a cost-effective replacement of more expensive (13)C- and (15)N-labeled reagents.

MeSH terms

Chromatography, High Pressure Liquid
Deuterium / chemistry*
Indicators and Reagents / chemistry
Proteins / analysis*
Proteins / chemistry
Staining and Labeling

Substances

Indicators and Reagents
Proteins
Deuterium