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Invest Ophthalmol Vis Sci. 2009 Nov;50(11):5247-50. doi: 10.1167/iovs.08-3117. Epub 2009 Jun 3.

Glaucoma filtration surgery and retinal oxygen saturation.

Author information

1
Department of Ophthalmology, University of Iceland/LandspĂ­tali-University Hospital, Reykjavik, Iceland.

Abstract

PURPOSE:

Glaucoma may involve disturbances in retinal oxygenation and blood flow. The purpose of this study was to measure the effect of glaucoma filtration surgery on retinal vessel oxygen saturation.

METHODS:

A noninvasive spectrophotometric retinal oximeter was used to measure hemoglobin oxygen saturation in retinal arterioles and venules before and after glaucoma filtration surgery. Twenty-five consecutive patients were recruited, and 19 had adequate image quality. Fourteen underwent trabeculectomy and five glaucoma tube surgery. Twelve had primary open-angle glaucoma and seven had exfoliative glaucoma. IOP decreased from 23 +/- 7 to 10 +/- 4 mm Hg (mean +/- SD, P = 0.0001).

RESULTS:

Oxygen saturation increased in retinal arterioles from 97% +/- 4% to 99% +/- 6% (n = 19; P = 0.046) after surgery and was unchanged in venules (63% +/- 5% before surgery and 64% +/- 6% after, P = 0.76). There were no significant changes in saturation in the fellow eyes (P > 0.60). The arteriovenous difference was 34% before and 36% after surgery (P = 0.35).

CONCLUSIONS:

Glaucoma filtration surgery had almost no effect on retinal vessel oxygen saturation.

PMID:
19494205
DOI:
10.1167/iovs.08-3117
[Indexed for MEDLINE]

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