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Chemphyschem. 2009 Jul 13;10(9-10):1478-81. doi: 10.1002/cphc.200900245.

Topography and recognition imaging of protein-patterned surfaces generated by AFM nanolithography.

Author information

1
Institut für Biophysik, Johannes Kepler Universität, Altenberger Str. 69, 4040 Linz, Austria.

Abstract

Native-protein nanolithography is combined with topography and recognition imaging to synergistically use AFM tips to write and image nanoscale protein patterns on a surface (see picture). The approach is validated with different feedback modes, using surface-bound biotinylated bovine serum albumin (BSA) protein and AFM tips carrying streptavidin.

PMID:
19492391
DOI:
10.1002/cphc.200900245
[Indexed for MEDLINE]

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