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J Matern Fetal Neonatal Med. 2009 Sep;22(9):770-5. doi: 10.3109/14767050902926939.

Independent risk factors for cesarean section among women with thrombophilia.

Author information

1
Department of Obstetrics and Gynecology, Faculty of Health Sciences, Soroka University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.

Abstract

OBJECTIVE To determine the prevalence of cesarean section (CS) in pregnant women with a diagnosis of thrombophilia and to identify risk factors for CS.

STUDY DESIGN:

The women were recognized by an ICD-9 code from a computerized database. Maternal records were reviewed between the years 2000 and 2005. Pregnancy characteristics of 86 women with thrombophilia were compared according to the mode of delivery: CS (n = 18) versus vaginal delivery (n = 68).

RESULTS:

The prevalence of CS in the study population was 21% (18/86). Women with CS had a lower gestational age at delivery (P = 0.019), lower birth weight (P = 0.048), higher incidence of the following: preterm delivery (P < 0.001), gestational hypertension (P = 0.028), intrauterine growth retardation/antepartum death/placental abruption (P = 0.065) and non-reassuring fetal heart rate (NRFHR) monitoring (P < 0.001) compared to those with vaginal delivery. In a multiple logistic regression analysis only NRFHR monitoring, birth weight and malpresentation remained statistically significant.

CONCLUSION:

CS in women with thrombophilia are associated with common obstetrical causes rather than specific thrombophilia dependent factors.

PMID:
19488939
DOI:
10.3109/14767050902926939
[Indexed for MEDLINE]

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