Send to

Choose Destination
Eur J Dermatol. 2009 Sep-Oct;19(5):504-6. doi: 10.1684/ejd.2009.0712. Epub 2009 Jun 2.

Neurosyphilis manifesting as lightning pain.

Author information

Department of Neurology, Second Affiliated Hospital, College of Medicine, Zhejiang, University, 88 Jiefang Road, Hangzhou China. 310009.


The large scale use of antibiotics in recent years has changed the face of neurosyphilis, as it has been accompanied by a drop in incidence and frequent replacement of typical forms of presentation with atypical or masked forms. Herein, we describe three patients who presented initially with intermittent stabbing, or lightning-like pains in the extremities that lasted for several years, who were subsequently diagnosed as having neurosyphilis during a clinical evaluation. The clinical symptoms underlying neurosyphilis are complex, rendering diagnosis and treatment difficult. Therefore clinicians must learn to recognize these symptoms to improve patient outcomes.

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for John Libbey Eurotext
Loading ...
Support Center